Custom Peptides
Cayman Chemical 1 2 3TrIundecnoyl GlycRol 10mg
A triacylglycerol; dietary administration prevents fasting-induced decreases in plasma glucose, alanine, and insulin levels, as well as the ratio of insulin to glucagon, in rats
Cayman Chemical ReldesemtIv 10mg
An activator of fast skeletal troponin; increases ATPase activity in isolated rabbit psoas muscle myofibril preparations (AC40 = 0.6 µM); selective for fast skeletal troponin over cardiac and slow skeletal troponin; selective for fast skeletal troponin over a panel of 79 enzymes, receptors, ion channels, and transporters at 100 µM; increases muscle tension in a skinned fast skeletal muscle fiber assay (DF30 = 0.8 µM); increases running time in the rotarod test, indicating increased exercise performance, in a rat model of heart failure-induced skeletal myopathy at 10 mg/kg, p.o.
Cayman Chemical BromoDragonFLYhydroCLOrId 10mg
An analytical reference standard categorized as a phenethylamine; has been associated with fatalities and acute overdoses; induces the head-twitch response in mice, indicating hallucinogenic potential; intended for research and forensic applications
Cayman Chemical 4methylNMethylbuphedron 10mg
A para-methyl analog of buphedrone with an aminomethyl addition; intended for research and forensic applications
Cayman Chemical AdIpoylCoenzyme AsodIM sa 10mg
A medium-chain acyl CoA; an intermediate in the peroxisomal β-oxidation of dicarboxylic acids; an intermediate in the biosynthesis of adipic acid in genetically modified E. coli
Cayman Chemical U-ContoxInacetate 10mg
A conotoxin and an inhibitor of Nav1.4 receptors; inhibits Nav1.4 in HEK293 cells (IC50 = 2.3 nM for the rat channel); inhibits rat Nav1.2 channels in HEK293 cells at 500 nM and is an antagonist of a7 nAChRs and a4ß2 and a3ß2 subunit-containing nAChRs in Xenopus oocytes expressing the human receptors (IC50s = 22, 2.9, and 0.45 µM, respectively); reduces global nerve action potential in isolated mouse sciatic nerves in a concentration-dependent manner; inhibits contraction in isolated mouse hemidiaphragm muscles (IC50 = 46 nM)
Cayman Chemical EpIberberIn 10mg
An alkaloid with diverse biological activities; inhibits the activities of AChE, BChE, and BACE1 (IC50s = 1.07, 6.03, and 8.55 µM, respectively); scavenges peroxynitrite radicals in a cell-free assay (IC50 = 16.83 µM); is cytotoxic to HepG2 HCC cells at 100 µM; reduces serum total cholesterol and LDL-cholesterol levels in Syrian golden hamsters fed a high-fat and high-cholesterol diet at 70 mg/kg
Cayman Chemical ngenol-3-ngelate 10mg
A hydrophobic diterpene ester that rapidly induces cell death in proliferating keratinocytes through plasma membrane and mitochondrial disruption; causes inflammation due, at least in part, to activation of PKC, leading to antibody-dependent cellular cytotoxicity
Cayman Chemical SaIkosaponIn C 10mg
A saikosaponin with anti-inflammatory and analgesic activities; reduces basal PGE2 production in isolated rat peritoneal macrophages at 100 UG/ml; decreases acetic acid-induced writhing in SART mice at 5 mg/kg per day
Cayman Chemical BIOnT FluorIn Fragmnt lbr 10mg
Customers are supplied with the following data package for EAch fragment purchases: • Aqueous buffer 19F NMR raw data file • Aqueous buffer 1H NMR raw data file • 19F NMR chemical shifts • Structures and physiochemical properties in an sd file The parameters used in the design of the library are: • Heavy atoms ≤ 21 • clogP ≤ 3 • Hydrogen bond donors ≤ 2 • Hydrogen bond acceptors ≤ 4 • tPSA ≤ 72 • Rotatable bonds ≤ 3
Cayman Chemical OxychlororaphIn 10mg
A microbial metabolite with diverse biological activities; cytotoxic to A549, HeLa, and SW480 cancer cells (IC50s = 32-40 μM); halts the cell cycle at the G1 phase and induces apoptosis in A549 cells; active against Streptomyces bacteria and T. mentagrophytes, E. floccosum, C. albicans, M. audouini, and B. dermatitidis fungi from 12.5 to 50 ppm
Cayman Chemical 2 4DImethylethcathInonhyd 10mg
A disubstituted analog of ethcathinone; intended for forensic and research purposes
Cayman Chemical MetIprnolol 10mg
A β-AR antagonist; binds to primary rabbit iris and ciliary body homogenates (Ki = 34 nM); inhibits isoproterenol-induced relaxation in guinea pig atrium and fenoterol-induced relaxation in rat uterus (pA2s = 8.3 and 8.4, respectively); inhibits anoxia-induced cell death in primary rat retinal cells and sodium nitroprusside-induced lipid peroxidation in rat primary retinal homogenates (100 μM); decreases α-chymotrypsin-induced increases in IOP in rabbits when administered topically to the eye at a dose of 0.3%; inhibits the blinking response to ocular tactile stimulation in rabbits when administered topically to the eye at a dose of 0.6%
Cayman Chemical KaempfRol 3nohSpRIdosID 10mg
A flavonoid with antioxidant and antidiabetic activities; scavenges DPPH radicals (IC50 = 79.6 UG/ml); increases glucose uptake in isolated rat soleus muscle at 1 and 100 nM; increases glycogen synthesis in isolated rat soleus muscle at 1 µM; reduces serum glucose levels in a rat model of alloxan-induced diabetes at 100 mg/kg
